Pregnancy and Diabetes, Dementia Risk, Pediatric Ketoacidosis

What are the top 10 research priorities for international researchers working in the field of women’s health and diabetes? According to a recent report in HCPLive®, British researchers surveyed both healthcare providers and women with diabetes to determine which areas of unmet need could benefit from more research.

The first phase of the project involved a survey, which received 466 responses. In a second phase, the participants met for a workshop to reach a consensus on the main priorities.

The top 10 research priorities for diabetes and pregnancy are:

Diabetes technology Optimal testing for diabetes during pregnancy Diet and lifestyle Interventions Emotional and well-being needs of women with diabetes before to post-pregnancy Safe delivery in the long term Post-natal care and support needs of women Diagnosis and treatment late in pregnancy Prevention of other types of diabetes in women with gestational diabetes Women labor and birth experiences and choices Improving pregnancy planning

Risk of dementia associated with earlier onset of diabetes

A recently published study in JAMA found an association between an increased risk of dementia the younger the patient was with type 2 diabetes (T2D). In a prospective cohort study of 10,095 participants in the United Kingdom, the adjusted analysis found that at age 70, the hazard ratio for each 5-year age at which T2D started was 1.24 (95% CI, 1.06-1, 46).

Researchers were only able to make a few hypotheses for the association, such as a link between brain metabolic dysfunction and insulin resistance, as well as higher rates of hypoglycemia with diabetes treatment, increasing the risk of dementia.

The study was also reported in HCPLive®.

Diabetic ketoacidosis increases in children during COVID-19

According to a recent study in Diabetes Care, there is an increase in the number of children with T2D presenting with diabetic ketoacidosis (DKA).

The study was conducted at the Children’s Hospital of Los Angeles, where researchers examined medical records of patients with newly-emerging T2D between March and August 2018 to 2020. The results showed a large spike in these cases, from 9% in 2018, to 3% in 2019, and then by 20% in 2020 (P = .029).

The researchers theorized that because of the pandemic, children may have missed pediatrician appointments, had less physical activity, or had less access to healthy food. There may also be a biological link between the virus and diabetes, they said.

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